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Item Details
Title:
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ASPARTIC ACID PROTEASES AS THERAPEUTIC TARGETS
ASPARTIC ACID PROTEASES |
By: |
Arun K. Ghosh (Editor), Joseph P. Vacca (Editor), Raimund Mannhold |
Format: |
Hardback |
List price:
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£183.95 |
We currently do not stock this item, please contact the publisher directly for
further information.
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ISBN 10: |
3527318119 |
ISBN 13: |
9783527318117 |
Publisher: |
WILEY-VCH VERLAG GMBH |
Pub. date: |
25 August, 2010 |
Series: |
Methods and Principles in Medicinal Chemistry |
Pages: |
640 |
Description: |
In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. |
Synopsis: |
In this ground-breaking practical reference, the family of aspartic acid proteases is described from a drug developer's perspective. The first part provides a general introduction to the family of aspartic acid proteases, their physiological functions, molecular structure and inhibition. Parts two to five present various case studies of successful protease inhibitor drug design and development, as well as current and potential uses of such inhibitors in pharmaceutical medicine, covering the major therapeutic targets HIV-1 protease, renin, beta-secretase, gamma-secretase,plasmepsins and fungal proteases. A ready reference aimed primarily at professionals in the pharmaceutical industry, as well as for anyone studying proteases and their function. |
Illustrations: |
Illustrations |
Publication: |
Germany |
Imprint: |
Wiley-VCH Verlag GmbH |
Returns: |
Returnable |
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