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Item Details
| Title:
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PATHOBIOLOGY OF ALZHEIMER'S DISEASE
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| By: |
Peter Jenner, Alison M. Goate (Editor), Frank Ashall (Editor) |
| Format: |
Hardback |
| List price:
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£135.00 |
| Our price: |
£121.50 |
| Discount: |
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| You save:
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£13.50 |
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| ISBN 10: |
0122869656 |
| ISBN 13: |
9780122869655 |
| Availability: |
This item will be printed on demand and will usually be dispatched within 10 days.
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| Stock: |
Currently 0 available |
| Publisher: |
ELSEVIER SCIENCE PUBLISHING CO INC |
| Pub. date: |
17 October, 1995 |
| Series: |
Neuroscience Perspectives |
| Pages: |
256 |
| Description: |
Advances in our understanding of the pathobiology of Alzheimer's disease, will lead to drugs aimed at prevention rather than cure. This book covers some of the most important of these advances. It also describes cell biological approaches that piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease. |
| Synopsis: |
Neuroscience Perspectives provides multidisciplinary reviews of topics in one of the most diverse and rapidly advancing fields in the life sciences.Whether you are a new recruit to neuroscience, or an established expert, look to this series for 'one-stop' sources of the historical, physiological, pharmacological, biochemical, molecular biological and therapeutic aspects of chosen research areas.The last decade has seen tremendous advances in our understanding of the pathobiology of Alzheimer's disease. These will lead to the first generation of drugs aimed at prevention rather than cure. This book covers some of the most important and exciting of these advances, with chapters written by many of the leading researchers in the field.With genetic studies as a backbone to this volume many chapters are devoted to the function and regulation of amyloid b-protein precursor (APP) and apolipoprotein E (ApoE). Other chapters describe cell biological approaches helping to piece together the link between the genetic alterations and the phenotype we call Alzheimer's disease.Although APP and its proteolytic cleavage product, amyloid b-protein, do not answer all the questions, detailed research into this system has undoubtedly increased our knowledge of the pathobiology of AD and has lead to the identification of other risk factors. Understanding the role of ApoE in the pathology of Alzheimer's disease promises to open a whole new field in AD research. |
| Publication: |
US |
| Imprint: |
Academic Press Inc |
| Returns: |
Non-returnable |
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