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Item Details
| Title:
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TYROSINE PHOSPHOPROTEIN PHOSPHATASES
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| By: |
Barry J. Goldstein |
| Format: |
Paperback |
| List price:
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£98.00 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0198502478 |
| ISBN 13: |
9780198502470 |
| Publisher: |
OXFORD UNIVERSITY PRESS |
| Pub. date: |
30 April, 1998 |
| Edition: |
2nd Revised edition |
| Series: |
Protein Profiles |
| Pages: |
272 |
| Description: |
Tyrosine phosphoprotein phosphatases are a family of enzymes found ubiquitously in cells, and are involved in a number of metabolic and signalling pathways. This volume explores their sequence, structure, and biochemical properties, providing a unique reference work for researchers. It also includes an extensive, categorized bibliography. |
| Synopsis: |
Tyrosine phosphoprotein phosphatases (PTPases) are found ubiquitously in cytosolic and particulate fractions of cells. They are unique in terms of their substrate sensitivity, neutral pH optimum, resistance to EDTA, and inhibition by low concentrations of zinc or vandanate. PTPases exert both positive and negative effects on a number of metabolic and signal transduction pathways. This volume explores the sequence, structure, and biochemical properties of PTPases, regulation of PTPase expression, substrate preferences and catalytic mechanisms, physiology, covalent modification, modification by chemical agents and proteolysis, and interactions with other proteins, peptides, and macromolecules. There is an extensive bibliography to assist the reader in further research. |
| Illustrations: |
10 line figures |
| Publication: |
UK |
| Imprint: |
Oxford University Press |
| Returns: |
Returnable |
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