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Item Details
Title: POST-TRANSLATIONAL PROCESSING
A PRACTICAL APPROACH
By: S. J. Higgins (Editor), B. D. Hames (Editor)
Format: Paperback

List price: £92.00


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ISBN 10: 0199637954
ISBN 13: 9780199637959
Publisher: OXFORD UNIVERSITY PRESS
Pub. date: 20 May, 1999
Series: Practical Approach Series 203
Pages: 338
Description: Translation of mRNA by a ribosome produces a poly-peptide known as the primary transcript. Before this primary transcript is transported to its final location to perform its intended function, it must first be altered in various ways. These alterations are collectively known as post- translational modification and are vital to the correct location and functioning of proteins.
Synopsis: Post - Translational Modification: A Practical Approach and its companion volume Protein Expression: A Practical Approach form the final part of the PAS mini-series on protein synthesis and processing. This volume begins with a chapter on protein sequencing followed by a chapter on protein folding and import into organelles. The next three chapters cover the three major forms of covalent modification: phosphorylation, glycosylation, and lipid modification. Proteolytic processing the is the next topic and the final two chapters are concerned with protein turnover in mammalian cells and yeast. This book is a comprehensive volume of the best current methodology and is designed to be used at the bench or away from the bench to gain insight into future experimental approached.
Illustrations: 9 halftones, 13 line figures
Publication: UK
Imprint: Oxford University Press
Returns: Returnable
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