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Item Details
Title: PROTEIN KINASE CK2
By: Lorenzo A. Pinna
Format: Hardback

List price: £181.95
Our price: £163.76
Discount:
10% off
You save: £18.19
ISBN 10: 0470963034
ISBN 13: 9780470963036
Availability: Usually dispatched within 1-3 weeks.
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Publisher: JOHN WILEY AND SONS LTD
Pub. date: 14 December, 2012
Series: Wiley-IUBMB Series on Biochemistry and Molecular Biology
Pages: 480
Description: * Explores the role of CK2 as a target in cancer treatment * Written by an international group of experts in the field * Covers the molecular, structural and functional aspects of CK2 * Includes appendix with information on the implication of CK2 in non-oncologic diseases .
Synopsis: Protein kinases play a critical role in cellular processes that impact overall organismal health and function. Of the kinases that collectively make up the Human Kinome, CK2 has garnered special attention because of its significant role in the generation of the human phosphoproteome. The role CK2 plays in the development of cancer and other disease has also made it of significant interest for its potential role in future therapeutics. Protein Kinase CK2 comprehensively brings together the varied work being done on this critical enzyme. Protein Kinase CK2 is logically divided into three sections. The first section reviews key molecular and structural aspects of the enzyme. The second section looks at functional aspects of CK2 and the diverse roles it plays in cellular development, function, and health. The final section focuses on CK2 and cancer, looking at the impacts of the kinase on neoplastic development and its rapidly developing role as a therapeutic agent. With contributions from the world s leading experts in the field, Protein Kinase CK2 will serve as an invaluable guide to the expanding and vibrant body of research being performed on this enzyme.This will be an essential volume for anyone working in the fields of biochemistry, protein science, signal transduction, metabolic regulation, and cancer biology and therapeutics. Editor Lorenzo A. Pinna is Professor in the Department of Biomedical Sciences at the University of Padua, Padua, Italy. Also Published in the Wiley-IUBMB Series on Biochemistry and Molecular Biology: Plant Phenolics and Human Health: Biochemistry, Nutrition, and Pharmacology Edited by Cesar G. Fraga ISBN: 978-0-470-28721-7
Illustrations: Illustrations
Publication: US
Imprint: Wiley-Blackwell
Returns: Returnable
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