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Item Details
Title: COMBINATIONAL CHEMISTRY
SYNTHESIS AND APPLICATION
By: Stephen R. Wilson (Editor), Anthony W. Czarnik (Editor)
Format: Hardback

List price: £165.95
Our price: £149.36
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ISBN 10: 047112687X
ISBN 13: 9780471126874
Availability: Usually dispatched within 1-3 weeks.
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Publisher: JOHN WILEY AND SONS LTD
Pub. date: 8 April, 1997
Pages: 288
Description: A complete overview of the exciting new field of combinatorial chemistry--an area of research that is revolutionizing drug development by allowing chemists to make and test millions of chemical compounds quickly and inexpensively through computer advances and laboratory automation.
Synopsis: The new time-saving revolution in drug discovery. Combinatorial chemistry, a method for synthesizing millions of chemical compounds much faster than usual, is becoming one of the most useful technical tools available to chemists and researchers working today. Using current advances in computer and laboratory techniques, combinatorial chemistry has freed professionals from the drudgery of piecemeal experimental work and opened new creative possibilities for experimentation. Combinatorial Chemistry: Synthesis and Application details critical aspects of the technique, featuring the work of some of the world's leading chemists, many of whom played a key role in its development.Including examples of both solution-phase and solid-phase approaches as well as the full complement of organic chemistry technologies currently available, the book describes: Concepts and terms of combinatorial chemistry Polymer-supported synthesis of organic compounds Macro beads as microreactors Solid-phase methods in combinatorial chemistry Encoded combinatorial libraries, including Rf-encoding of synthesis beads Strategies for combinatorial libraries of oligosaccharides Combinatorial libraries of peptides, proteins, and antibodies using biological systems. While combinatorial chemistry originated in peptide chemistry, this volume has deliberately focused on nonpeptide organic applications, illustrating the technique's wide uses. Combinatorial Chemistry introduces organic, medicinal, and pharmaceutical chemists as well as biochemists to this exciting, cost-effective, and practical technique, which has unlocked creative potential for the next millennium.
Illustrations: Illustrations
Publication: US
Imprint: John Wiley & Sons Inc
Returns: Returnable
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