| Title:
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GENERATION AND INTERPRETATION OF MORPHOGEN GRADIENTS
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| By: |
James Briscoe (Editor), Jean-Paul Vincent (Editor), Peter Lawrence (Editor) |
| Format: |
Hardback |
| List price:
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£84.00 |
| Our price: |
£75.60 |
| Discount: |
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| You save:
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£8.40 |
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| ISBN 10: |
0879698810 |
| ISBN 13: |
9780879698812 |
| Availability: |
Usually dispatched within 1-3 weeks.
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| Stock: |
Currently 0 available |
| Publisher: |
COLD SPRING HARBOR LABORATORY PRESS,U.S. |
| Pub. date: |
22 March, 2010 |
| Pages: |
900 |
| Synopsis: |
Signalling by morphogens such as the Hedgehog family, Notch, Wingless/Wnt and various growth factors is essential during embryogenesis. The establishment of concentration gradients of these morphogens plays a key role during developmental patterning in all multicellular organisms, assuring that distinct cell/tissue types and organs appear at the right place in the right time during embryogenesis. Regulation of morphogen synthesis, trafficking and diffusion are all known to play a part in setting up these gradients, and a complex web of signaling mechanisms ensures that specific responses occur at the correct threshold concentration in the recipient cells whose fate depends on these morphogens. |
| Illustrations: |
Illustrations |
| Publication: |
US |
| Imprint: |
Cold Spring Harbor Laboratory Press,U.S. |
| Returns: |
Returnable |