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Item Details
Title: PRION DISEASES
By: Richard Baker
Format: Hardback

List price: £129.99
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ISBN 10: 0896033422
ISBN 13: 9780896033429
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Publisher: HUMANA PRESS INC.
Pub. date: 17 April, 1996
Edition: 1996 ed.
Series: Methods in Molecular Medicine v. 3
Pages: 319
Description: This volume discusses such areas as the surveillance of prion diseases, methods of preventing infection by prion diseases, neuropathological diagnosis of prion diseases, utilization of immunotechniques for the diagnosis of prion diseases, and the pathogenesis of prion disease.
Synopsis: Harry Baker and Rosalind Ridley have done an admirable job in assem- bling this collection of articles that describe the methodology frequently used to study a group of CNS illnesses often referred to as the "prion diseases." Research on prions and the disorders that they cause has progressed relatively rapidly over the last decade since the discovery of the prion protein (PrP) that allowed the application of modem molecular biological and genetic tools. The power of these techniques is awesome and their use in deciphering the once mysterious prion diseases has brought a wealth of new information. Although prions are unprecedented pathogens, appearing to consist only of PrPSc molecules, the diseases that they cause are no less remarkable. The prion diseases in animals include scrapie of sheep and goats as well as "mad cow" disease or bovine spongiform encephalopathy (BSE). In the United King- dom, the epidemic of BSE has heightened public awareness of this previously obscure group of diseases such that any work in the field is likely to stir up interest in the media and become a subject of public debate.It has been diffi- cult for British investigators to work on prion diseases without being involved in these controversies. As such, several chapters have been included that deal with political and social issues surrounding prion diseases. The human prion diseases present an equally fascinating saga in which these CNS degenerations present as genetic, sporadic, and infectious illnesses.
Illustrations: biography
Publication: US
Imprint: Humana Press Inc.
Returns: Returnable
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