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Item Details
| Title:
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BRAIN IMMUNE SYSTEM SIGNAL MOLECULES IN PROTECTION FROM AEROBIC AND ANAEROBIC INFECTIONS
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| By: |
Armen Galoyan |
| Format: |
Paperback |
| List price:
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£139.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
1489988157 |
| ISBN 13: |
9781489988157 |
| Publisher: |
SPRINGER-VERLAG NEW YORK INC. |
| Pub. date: |
17 July, 2014 |
| Edition: |
2012 ed. |
| Series: |
Advances in Neurobiology 6 |
| Pages: |
200 |
| Description: |
This book surveys neuroimmune function, and describes antibacterial, neuroprotective and neuroregenerative properties of proline-rich polypeptides. Reviews the action of galarmin in targeting anthrax, tuberculosis, staphylococcus and other pathogens. |
| Synopsis: |
Proline-rich polypeptides - in particular (PRP-1) galarmin and its structural analogues - are, when isolated from the neurosecretory granules of neurohypophysis of humans and animals, a new type of hypothalamic peptides. They work against aerobic, anaerobic, gram-positive, and gram-negative microorganisms in vivo, and do not have etiotropic properties. They are unique and capable substitutes to antibiotics, and, moreover, may be effective against strains, such as MRSA, that develop resistance to antibiotics. Galarmin, a component of the brain neuroendocrine system produced by the neurosecretory cells of hypothalamus, possesses immunomodulative, neuroprotective, antioxidant, antitumorigenic and hematopoietic properties. Moreover, galarmin and its structural analogues are powerful anti-inflammatory compounds. In addition to presenting a full overview of the neuroimmune system, it emphasizes the antibacterial, neuroprotective, and neuroregenerative properties of proline-rich polypeptides. It investigates the mechanism of galarmin's action during different infectious processes, where it targets such dangerous pathogens as Bacillus anthracis, Clostridium perfringens, Mycobacterium tuberculosis, and Methycillin resistant Staphylococcus aureus. This research is important from both a theoretical and a clinical point of view, creating new prospects for the modern pharmaceutical industry and neuroendocrine, neuroimmunological sciences.Dr. Galoyan is a pioneer of the specialized field of neuroimmunology. During his 45-year long career, he has discovered a neuroendocrine immune system of the brain and identified a new type of brain cytokines: proline-rich polypeptides. The most important of these, PRP-1 (galarmin) has been shown to possess antibacterial properties and protect from certain neurotoxins. |
| Illustrations: |
41 Tables, black and white; XVI, 200 p. |
| Publication: |
US |
| Imprint: |
Springer-Verlag New York Inc. |
| Returns: |
Returnable |
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