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Item Details
Title: SIGNALING IN THE HEART
By: Jose Marin-Garcia
Format: Paperback

List price: £149.99


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 1489995765
ISBN 13: 9781489995766
Publisher: SPRINGER-VERLAG NEW YORK INC.
Pub. date: 1 October, 2014
Edition: 2011 ed.
Pages: 507
Description: This volume offers comprehensive coverage of commonalities and differences in signaling pathway elements in a broad spectrum of cardiovascular diseases, including heart failure, arrhythmias to atherosclerosis, hypertension, diabetes and metabolic syndrome.
Synopsis: Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in signaling pathways are contributing factors in the development and progression of a broad spectrum of diseases, ranging from dysrhythmias and atherosclerosis to hypertension and the metabolic syndrome. Targeting specific components of these signaling pathways has been shown to be effective in preclinical studies with significant therapeutic impact. This book brings together current knowledge in cardiovascular cell signal transduction mechanisms, advances in novel therapeutic approaches to improve cardiac function, and discussion of future directions. Presented from a post-genomic perspective, this exciting book introduces important new ideas in cardiovascular systems biology. It is an invaluable reference for cardiology researchers and practitioners.
Illustrations: 27 Tables, black and white; XX, 507 p.
Publication: US
Imprint: Springer-Verlag New York Inc.
Returns: Returnable
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