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Item Details
Title: DYNEMICIN A, UNCIALAMYCIN AND ANALOGUES
By: Daniel Best, Mickael Jean, Pierre Weghe
Format: Hardback

List price: £76.00
Our price: £68.40
Discount:
10% off
You save: £7.60
ISBN 10: 1785481509
ISBN 13: 9781785481505
Availability: This item will be printed on demand and will usually be dispatched within 10 days.
 Delivery rates
Stock: Currently 0 available
Publisher: ISTE PRESS LTD - ELSEVIER INC
Pub. date: 14 June, 2016
Pages: 144
Synopsis: Enediynes are natural products with highly active cytotoxicity and antibacterial activity, and thus have significant potential in the development of anti-cancer treatments. However, they are not readily available and can degrade rapidly during isolation; one solution is to produce them using total synthesis. Dynemicin A and uncialamycin are two such enediynes, with similar structures, for which total synthesis has been achieved. This book presents the isolation and preparation of these two compounds and their analogues through various synthesis strategies. Details of the structural elements essential to their anti-cancer activity are presented, with the objective of explaining and optimizing their biological activities and potential development as drugs.
Publication: UK
Imprint: ISTE Press Ltd - Elsevier Inc
Returns: Returnable
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