| Title:
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ALTERNATIVE SPLICING AND DISEASE
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| By: |
Philippe Jeanteur (Editor) |
| Format: |
Hardback |
| List price:
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£199.99 |
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| ISBN 10: |
3540344489 |
| ISBN 13: |
9783540344483 |
| Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
| Pub. date: |
3 August, 2006 |
| Series: |
Progress in Molecular and Subcellular Biology 44 |
| Pages: |
257 |
| Description: |
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. However, this process is not unequivocal but can follow alternate pathways. Alternative splicing of a given transcript can therefore yield several distinct mRNAs encoding as many different proteins. This book talks about this alternate pathway. |
| Synopsis: |
Splicing of primary RNA transcript is a quasi-systematic step of gene expression in higher organisms. This is the first book to highlight the medical implications, i.e. diseases, caused by alternative splicing. Alternative splicing not only vastly increases protein diversity but also offers numerous opportunities for aberrant splicing events with pathological consequences. The book also outlines possible targets for therapy. |
| Illustrations: |
6 Tables, black and white; 2 Illustrations, color; 24 Illustrations, black |
| Publication: |
Germany |
| Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
| Returns: |
Returnable |