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Item Details
Title: ENDOTHELIN AND ITS INHIBITORS
By: Timothy Warner (Editor), B. Battistini (Editor)
Format: Hardback

List price: £253.00


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ISBN 10: 3540679855
ISBN 13: 9783540679851
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Edition: 2000 ed.
Series: Handbook of Experimental Pharmacology v. 152
Pages: 556
Description: Since its characterisation in 1988, endothelin research has moved rapidly. This volume contains reviews that cover every area of our knowledge regarding the endothelins (Endothelin production, actions of endothelins, receptors, signalling pathways, endothelin and diseases, endothelin antagonists, endothelin converting enzyme inhibitors).
Synopsis: Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.
Illustrations: 73 figs., 17 tabs.
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Non-returnable
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