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Item Details
| Title:
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PHARMACOTHERAPY OF PULMONARY HYPERTENSION
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| By: |
Marc Humbert (Editor), Oleg V. Evgenov (Editor), Johannes-Peter Stasch (Editor) |
| Format: |
Hardback |
| List price:
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£219.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3642386636 |
| ISBN 13: |
9783642386633 |
| Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
| Pub. date: |
4 October, 2013 |
| Edition: |
2013 ed. |
| Series: |
Handbook of Experimental Pharmacology 218 |
| Pages: |
576 |
| Description: |
Pharmacotherapy of Pulmonary Hypertension |
| Synopsis: |
This volume focuses on current evidence-based pharmacological treatments of various forms of pulmonary hypertension and provides a comprehensive review of the latest developments in this area. The first part of the book covers the definition, classification, pathophysiology, pathology, biomarkers and animal models of the disease, thus laying the conceptual basis for what follows. The middle section provides an overview of the established therapies, such as calcium channel blockers, prostanoids, endothelin receptor antagonists, phosphodiesterase-5 inhibitors and inhaled nitric oxide. The last section explores novel pathways and emerging therapeutic approaches including soluble guanylate cyclase stimulators, Rho-kinase inhibitors, inhibitors of serotonin receptors and transporters, peptide growth factors, vasoactive peptides, modulators of redox equilibrium and cyclic nucleotide homeostasis, as well as immunosuppressive and anti-proliferative agents. Particular attention is given to the clinical applications of these experimental therapies, that are on the horizon. The book thus spans the continuum from basic science to clinical applications. |
| Illustrations: |
10 black & white illustrations, 56 colour illustrations, biography |
| Publication: |
Germany |
| Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
| Returns: |
Non-returnable |
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