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Item Details
Title: ENDOTHELIN AND ITS INHIBITORS
By: Timothy Warner (Editor)
Format: Paperback

List price: £54.99


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 3642632378
ISBN 13: 9783642632372
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Pub. date: 14 February, 2012
Edition: Softcover reprint of the original 1st ed. 2001
Series: Handbook of Experimental Pharmacology 152
Pages: 560
Description: With contributions by numerous experts
Synopsis: Recent publications have addressed specific aspects of the endothelins, such as their roles in disease or the importance of endothelin receptors. However, in this book the entire field of endothelins is covered. This includes the pathways of endothelin production and their regulation, the local and systemic actions of endothelins, receptors for the endothelins and the signalling pathways employed, and the involvement of endothelins in a range of diseases. Attention is also paid to the development through chemistry, pharmacology and toxicology of endothelin antagonists and endothelin-converting enzyme inhibitors, with mention of all the important members of these drug classes. This leads to well-rounded discussions of the potential therapeutic benefit of endothelin inhibitors.
Illustrations: 15 black & white illustrations, 3 colour illustrations, 17 black & white
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Returnable
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