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Item Details
Title: A HANDBOOK OF TRANSCRIPTION FACTORS
By: Timothy R. Hughes (Editor)
Format: Hardback

List price: £219.99


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ISBN 10: 9048190681
ISBN 13: 9789048190683
Publisher: SPRINGER
Pub. date: 16 December, 2010
Edition: 2011 ed.
Series: Subcellular Biochemistry 52
Pages: 306
Description: Written from a genome-based perspective, this volume provides an objective overview of transcription factor biochemistry. Topics include known transcription factor classes, origins and evolution of transcription factor types, and mechanisms of interaction with chromatin.
Synopsis: Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.
Illustrations: XIV, 306 p.
Publication: Netherlands
Imprint: Springer
Returns: Returnable
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