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Item Details
Title: UBIQUITIN-PROTEASOME PROTEOLYTIC SYSTEM, THE: FROM CLASSICAL BIOCHEMISTRY TO HUMAN DISEASES
By: Aaron J. Ciechanover (Editor), Maria Grazia Masucci (Editor)
Format: Hardback

List price: £79.00
Our price: £71.10
Discount:
10% off
You save: £7.90
ISBN 10: 9812381007
ISBN 13: 9789812381002
Availability: Reprinting. This item may be subject to delays or cancellation.
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Stock: Currently 0 available
Publisher: WORLD SCIENTIFIC PUBLISHING CO PTE LTD
Pub. date: 19 November, 2002
Series: Recent Advances In Human Biology 9
Pages: 240
Description: Ubiquitin-proteosome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes. This text tells the story of the ubiquitin system as we know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, and more.
Synopsis: Ubiquitin-proteasome-dependent proteolysis is central to an incredible multitude of processes in all eukaryotes, including the cell cycle, cell growth and differentiation, embryogenesis, apoptosis, signal transduction, DNA repair, regulation of transcription and DNA replication, transmembrane transport, endocytosis, stress responses, antigen presentation and other aspects of the immune response, the functions of the nervous system including circadian rhythms, axon guidance and acquisition of memory.This book tells the story of the ubiquitin system as we currently know it: from the regulation of basic cellular processes to quality control and the pathogenetic mechanisms of disease, from X-ray crystallography of the 26S proteasome to the interaction between substrates and their ligases, to the development of mechanism-based drugs, and to target-specific aberrant processes.
Publication: Singapore
Imprint: World Scientific Publishing Co Pte Ltd
Returns: Returnable
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