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Item Details
| Title:
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PEPTIDE RECEPTORS, PART II
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| Volume: |
Volume 20 |
| By: |
Anders Bjorklund (Editor), T. Hokfelt (Editor), Patrice Quinton (Editor) |
| Format: |
Hardback |
| List price:
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£240.00 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0444505407 |
| ISBN 13: |
9780444505408 |
| Publisher: |
ELSEVIER SCIENCE & TECHNOLOGY |
| Pub. date: |
13 December, 2002 |
| Series: |
Handbook of Chemical Neuroanatomy |
| Pages: |
440 |
| Description: |
Covers six families of neuropeptide receptors for ligands ranging from peptides such as the opioids and neurotensin to isolated ones like the orexins. This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry. |
| Synopsis: |
Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complementwith chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry.Data derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-receptor complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis. |
| Publication: |
UK |
| Imprint: |
Elsevier Science Ltd |
| Returns: |
Non-returnable |
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