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Item Details
| Title:
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DOPAMINE TRANSPORTERS
CHEMISTRY, BIOLOGY, AND PHARMACOLOGY |
| By: |
Mark L. Trudell (Editor), Sari Izenwasser (Editor), Binghe Wang |
| Format: |
Hardback |
| List price:
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£134.95 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0470117907 |
| ISBN 13: |
9780470117903 |
| Publisher: |
JOHN WILEY AND SONS LTD |
| Pub. date: |
28 July, 2008 |
| Series: |
Wiley Series in Drug Discovery and Development |
| Pages: |
444 |
| Description: |
Both a reference source for researchers and a text for graduate students investigating the various aspects of the dopamine transporter (DAT), Dopamine Transporter: Chemistry, Biology, and Pharmacology includes aspects of chemistry, biology, and pharmacology and provides a strong general overview of this neurotransmitter. |
| Synopsis: |
Understanding the dopamine transporter can lead to new therapies for neurological disorders This book consolidates current information on the dopamine transporter (DAT) in relationto medicinal chemistry and synthesis, biology and pathology, and pharmacology. Because of DAT's role in diseases such as Parkinson's, schizophrenia, attention deficit hyperactivity disorder (ADHD), Tourette syndrome, and drug abuse (in particular, cocaine addiction), DAT research is an exploding field. Tremendous advances have been made toward understanding how it impacts a variety of neurological disease states and disorders. This reference provides a broad overview of current knowledge that is detailed enough to furnish a basic understanding of the biological, chemical, and pharmacological aspects of DAT in one comprehensive reference.With contributions from eminent scientists who are experts in their particular areas, Dopamine Transporters: Chemistry, Biology, and Pharmacology:* Reviews current studies and research in the areas of DAT function, pathological conditions, cloning, molecular structure, and electrochemical characterization* Covers findings in the medicinal chemistry of DAT-inhibitory ligands and substrates, discussing the chemical syntheses and summarizing the various structure-activity relationships of important classes of dopamine uptake inhibitors and dopamine releasers* Has chapters that focus on technologies for future DAT study, including imaging and in vivo and in vitro methodsThis is a hands-on reference for researchers, medicinal chemists, pharmacologists, and biologists working with DAT or related proteins and for students in related areas of study. |
| Illustrations: |
Illustrations (some col.) |
| Publication: |
US |
| Imprint: |
Wiley-Blackwell |
| Returns: |
Returnable |
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