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Item Details
| Title:
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LABEL-FREE TECHNOLOGIES FOR DRUG DISCOVERY
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| By: |
Matthew A. Cooper (Editor), Lorenz M. Mayr (Editor) |
| Format: |
Other digital |
| List price:
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£120.00 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
0470979127 |
| ISBN 13: |
9780470979129 |
| Publisher: |
JOHN WILEY AND SONS LTD |
| Pub. date: |
24 February, 2011 |
| Pages: |
348 |
| Description: |
Label-Free Technologies for Drug Discovery summarizes the latest and emerging developments in label-free detection systems, their underlying technology principles, and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery. |
| Synopsis: |
Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery summarises the latest and emerging developments in label-free detection systems, their underlying technology principles and end-user case studies that reveal the power and limitations of label-free in all areas of drug discovery. Label-free technologies discussed include SPR, NMR, high-throughput mass spectrometry, resonant waveguide plate-based screening, transmitted-light imaging, isothermal titration calorimetry, optical and impedance cell-based assays and other biophysical methods. The technologies are discussed in relation to their use as screening technologies, high-content technologies, hit finding and hit validation strategies, mode of action and ADME/T, access to difficult target classes, cell-based receptor/ligand interactions particularly orphan receptors, and antibody and small molecule affinity and kinetic analysis.Label-Free Technologies For Drug Discovery is an essential guide to this emerging class of tools for researchers in drug discovery and development, particularly high-throughput screening and compound profiling teams, medicinal chemists, structural biologists, assay developers, ADME/T specialists, and others interested in biomolecular interaction analysis. |
| Publication: |
US |
| Imprint: |
Wiley-Blackwell |
| Returns: |
Non-returnable |
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