MOLECULAR ONCOLOGY by Edward P. Gelmann (Editor), Charles L. Sawyers (Editor), Frank J. Rauscher (Editor) ( 9780521876629 )

Item Details

Title:

MOLECULAR ONCOLOGY
CAUSES OF CANCER AND TARGETS FOR TREATMENT

By:

Edward P. Gelmann (Editor), Charles L. Sawyers (Editor), Frank J. Rauscher (Editor)

Format:

Hardback

List price:

£177.00

Our price:

£154.88

Discount:

12.5% off

You save:

£22.12

ISBN 10:

0521876621

ISBN 13:

9780521876629

Availability:

Usually dispatched within 1-3 weeks.

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Stock:

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Publisher:

CAMBRIDGE UNIVERSITY PRESS

Pub. date:

19 December, 2013

Pages:

979

Description:

Reviews the origins of molecular oncology, including technologies for cancer analysis, key pathways in human malignancies, and available pharmacologic therapies.

Synopsis:

The genomic era has allowed enormous strides in our understanding of the molecular changes that underlie malignant transformation. Mutations have been discovered that are critical drivers of large cross-sections of human cancers. These discoveries have allowed us to find drugs that target these drivers and make important strides in treatment. Genomics and high-throughput technologies have illuminated the complexity of cancer and the facility with which cancers adapt during their natural history. The field is evolving rapidly with new discoveries and new drugs reported monthly. This book is a timely foundation for understanding in context the origins of molecular oncology and its future directions. The content reviews available technologies for the analysis of cancer tissues and genes; summaries of key oncogenic pathways from a molecular perspective; the technologies, pathways and targeted therapies of a wide range of human malignancies; and new pharmacologic therapies that have a common mechanistic target.

Illustrations:

48 b/w illus. 317 colour illus. 91 tables

Publication:

Imprint:

Cambridge University Press

Returns:

Returnable

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