 |
|
|
Item Details
| Title:
|
ANTIANGIOGENIC CANCER THERAPY
|
| By: |
Darren W. Davis (Editor), Roy S. Herbst (Editor), James L. Abbruzzese (Editor) |
| Format: |
Hardback |
| List price:
|
£290.00 |
| Our price: |
£261.00 |
| Discount: |
|
| You save:
|
£29.00 |
|
|
|
|
|
| ISBN 10: |
0849327997 |
| ISBN 13: |
9780849327995 |
| Availability: |
Usually dispatched within 1-3 weeks.
 Delivery
rates
|
| Stock: |
Currently 0 available |
| Publisher: |
TAYLOR & FRANCIS INC |
| Pub. date: |
25 July, 2007 |
| Pages: |
864 |
| Description: |
Offers information on the process of angiogenesis and its role in tumor growth and metastasis. This title compiles the work of experts to explore angiogenesis inhibitors under clinical investigation, as well as early agents used in preclinical studies. It discusses the unique aspects of targeting and inhibiting angiogenesis. |
| Synopsis: |
Top Investigators Explore the Complexities of Angiogenesis Cancer Research The targeting of tumor angiogenesis has evolved into one of the most widely pursued therapeutic strategies. However, as of yet, no antiangiogenic agent used as a monotherapy has demonstrated a survival benefit in a randomized Phase III trial. The combination of bevacizumab, the first FDA approved angiogenesis inhibitor, with cytotoxic regimens has led to survival benefits in cancer patients. This has raised important questions about the complexities inherent in the clinical application of angiogenesis inhibitors. Compiles the results of four decades of progress Integrating fundamental concepts with therapeutic strategies, Anti-Angiogenic Cancer Therapy promotes the idea that an understanding of the molecular and cellular regulation of angiogenesis leads to optimal therapeutic strategies and positive clinical results. It brings together contributions from leading researchers to provide the most authoritative and encyclopedic volume available on this subject.* Examines the role of angiogenesis in cancer, including strategies to prolong the nonangiogenic dormant state of human tumors, molecular mechanisms and cellular regulation of angiogenesis in solid tumors and hematologic malignancies, and the regulation of angiogenesis by the tumor microenvironment. * Covers specific molecular targets for inhibiting angiogenesis in cancer therapy. * Discusses clinical trial design and translational research approaches essential for identifying and developing effective angiogenesis inhibitors. * Outlines current understanding of the molecular biology of each cancer type followed by discussions that examine strategies for targeting angiogenesis in specific cancers. This volume celebrates progress made in four decades, and more importantly, it provides a clear indication of the complex biology that needs further investigation to realize the possibilities envisioned for this beneficial therapeutic modality. |
| Illustrations: |
109 black & white illustrations, 53 black & white tables, 34 black & white |
| Publication: |
US |
| Imprint: |
CRC Press Inc |
| Returns: |
Returnable |
|
|
|
 |
|
|
|
|
|
Little Worried Caterpillar (PB)
Little Green knows she''s about to make a big change - transformingfrom a caterpillar into a beautiful butterfly. Everyone is VERYexcited! But Little Green is VERY worried. What if being a butterflyisn''t as brilliant as everyone says?Join Little Green as she finds her own path ... with just a littlehelp from her friends.
|
|
All the Things We Carry PB
What can you carry?A pebble? A teddy? A bright red balloon? A painting you''ve made?A hope or a dream?This gorgeous, reassuring picture book celebrates all the preciousthings we can carry, from toys and treasures to love and hope. With comforting rhymes and fabulous illustrations, this is a warmhug of a picture book.
|
|
|
|