SYSTEMS BIOLOGY by Bernhard O. Palsson ( 9781107038851 ) - Books & Audio Books at Pickabook.co.uk

Item Details

Title:

SYSTEMS BIOLOGY
CONSTRAINT-BASED RECONSTRUCTION AND ANALYSIS

By:

Bernhard O. Palsson

Format:

Hardback

List price:

£56.99

Our price:

£51.29

Discount:

10% off

You save:

£5.70

ISBN 10:

1107038855

ISBN 13:

9781107038851

Availability:

Usually dispatched within 3-5 days.

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Stock:

Currently 2 available

Publisher:

CAMBRIDGE UNIVERSITY PRESS

Pub. date:

26 January, 2015

Pages:

550

Description:

The first comprehensive single-authored textbook on genome-scale models and the bottom-up approach to systems biology.

Synopsis:

Recent technological advances have enabled comprehensive determination of the molecular composition of living cells. The chemical interactions between many of these molecules are known, giving rise to genome-scale reconstructed biochemical reaction networks underlying cellular functions. Mathematical descriptions of the totality of these chemical interactions lead to genome-scale models that allow the computation of physiological functions. Reflecting these recent developments, this textbook explains how such quantitative and computable genotype-phenotype relationships are built using a genome-wide basis of information about the gene portfolio of a target organism. It describes how biological knowledge is assembled to reconstruct biochemical reaction networks, the formulation of computational models of biological functions, and how these models can be used to address key biological questions and enable predictive biology. Developed through extensive classroom use, the book is designed to provide students with a solid conceptual framework and an invaluable set of modeling tools and computational approaches.

Illustrations:

27 b/w illus. 244 colour illus. 45 tables

Publication:

Imprint:

Cambridge University Press

Returns:

Returnable

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