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Item Details
Title: COMPUTER TECHNIQUES IN PRECLINICAL AND CLINICAL DRUG DEVELOPMENT
By: Robert C. Jackson
Format: Electronic book text

List price: £97.00


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ISBN 10: 1420054198
ISBN 13: 9781420054194
Publisher: TAYLOR & FRANCIS INC
Pub. date: 23 July, 1996
Pages: 256
Synopsis: It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, "How can we use computational methods to improve the success rate in drug development?" Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.
Illustrations: 83 equations; 32 Tables, black and white
Publication: US
Imprint: CRC Press Inc
Returns: Non-returnable
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