Title:
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THE BIOLOGY OF GASTRIC CANCERS
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By: |
Timothy Wang (Editor), James G. Fox (Editor), Andy Giraud (Editor) |
Format: |
Paperback |
List price:
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£119.99 |
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ISBN 10: |
1441924051 |
ISBN 13: |
9781441924056 |
Publisher: |
SPRINGER-VERLAG NEW YORK INC. |
Pub. date: |
12 February, 2010 |
Edition: |
1st ed. Softcover of orig. ed. 2009 |
Pages: |
332 |
Description: |
This book is the first ever devoted to the basic biology of gastric cancer. Not only does it fully cover the history of clinical gastric cancer research, it also discusses cutting edge concepts in cancer stem cells, tumor microenvironment, chronic inflammation and genetic susceptibility. |
Synopsis: |
As someone who has spent nearly half his life wondering about the relationship between Helicobacter and gastric cancer, I find this textbook on the subject exciting and timely. In fact, I am not aware of any other volume that has been able to distil so much new knowledge into such a comprehensive account of a poorly understood field. Taking my own view, as a scientist placed in the middle of the spectrum between basic science and clinical medicine, I can see that the editors, Jim Fox, Andy Giraud, and Timothy Wang, provide a broad mix of expertise, which ensures that the subject is treated with the right balance. From clinicopathologic observations in humans, to epidemiology, through animal models, to molecular and cell biology, this team has hit the mark for most readers. Fox is a well-known leader in animal models with broad expertise. He pioneered the field with observations on Helicobacter species in animals, from the time when only one spiral gastric bac- rium was known, "Campylobacter pyloridis." Fox partners with Wang, whose team recently announced a dramatic advance in the field of carcinogenesis-the obser- tion that bone marrow-derived stem cells participate in the changes that become cancer. To this nice mix has been added Andy Giraud from my own country, who brings to the table some remarkable genetic models of gastric cancer based on alterations in the gp130/stat3-signaling pathway. |
Illustrations: |
37 black & white illustrations, 8 colour illustrations, 10 black & white |
Publication: |
US |
Imprint: |
Springer-Verlag New York Inc. |
Returns: |
Returnable |