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Item Details
Title: FRONTIERS IN BRAIN REPAIR
By: Rahul Jandial (Editor)
Format: Hardback

List price: £179.99


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ISBN 10: 1441958185
ISBN 13: 9781441958181
Publisher: SPRINGER-VERLAG NEW YORK INC.
Pub. date: 17 February, 2010
Edition: 2010 ed.
Series: Advances in Experimental Medicine and Biology v. 671
Pages: 134
Description: This volume provides a representative survey of the current science of brain repair. It offers a broad introduction into molecular imaging, stem cell biology, cell therapy, animal models, central nervous system malignancies, stroke, and neurodegeneration.
Synopsis: In the rapidly-evolving landscape of neurosciences, it is no easy task to select a limited array of topics to present in a text such as this. The current volume takes as its purpose to provide a representative survey of the current science of brain repair for those seeking to establish a foundation in the field or to replenish a prior knowledge base that may have lapsed in its currency. It also hopes to offer insights into what remains elusive to our collective investigations, defining the "frontiers" of brain repair for those that are currently immersed in the exciting intersection of biological advances and neuroscientific discoveries. In Chapter 1 the fundamentals of imaging transplanted cells is discussed with emphasis on animal models as well as the horizon for clinical trials. Then, detailed methods on the culture of neural stem cells is reviewed as a foundation for approaching therapeutic goals. Chapter 3 presents the broad scope of animal models that serve as the foundation for developmental and pre-clinical investigation, with mention of recent genetically engineered mouse models that represent the best models for studying disease development and treatment. Chapter 4 provides background on the delivery techniques to animals and patients that are available, providing vital information on the subtleties of technique necessary for optimal cellular grafting. Chapters 5 and 6 discuss new and evolving information on the origins of brain tumors and the indelible role of stromal and microenvironmental influences on oncogenesis and tumor progression. Subsequently, the utility of neural stem cells as cellular vehicles to deliver chemotherapeutics to broad neuropathology is reviewed. In Chapter 8 the scope of treating brain tumors is expanded beyond stem cells, to present the best biological interventions to improve upon current treatment options for brain malignancy. The last two chapters present a comprehensive review on stem cell and gene therapy options for treating cerebrovascular and neurovascular pathology. In amassing this collection, my intention has been to provide the reader with a broad introduction into molecular imaging, stem cell biology, cell therapy, animal models, central nervous system malignancies, stroke, and neurodegeneration. My hope is that Frontiers of Brain Repair will be the intellectual soil from which a deeply rooted and well-nourished vintage of neuroscience will arise.
Illustrations: 3 black & white tables, biography
Publication: US
Imprint: Springer-Verlag New York Inc.
Returns: Returnable
Some other items by this author:
100 CASE REVIEWS IN NEUROSURGERY (PB)
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BEST EVIDENCE FOR SPINE SURGERY (HB)
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CORE TECHNIQUES IN OPERATIVE NEUROSURGER
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CORE TECHNIQUES IN OPERATIVE NEUROSURGERY E-BOOK
FRONTIERS IN BRAIN REPAIR (PB)
LIFE LESSONS FROM A BRAIN SURGEON (HB)
LIFE LESSONS FROM A BRAIN SURGEON (PB)
LIFE ON A KNIFE''S EDGE (PB)
METASTATIC CANCER: CLINICAL AND BIOLOGICAL PERSPECTIVES
METASTATIC CANCER: CLINICAL AND BIOLOGICAL PERSPECTIVES (HB)
NEUROFITNESS BRAIN SURGEONS SECRETS (HB)
NEUROSURGICAL ESSENTIALS (PB)
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REGENERATIVE BIOLOGY OF THE SPINE AND SPINAL CORD (HB)
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