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Item Details
Title:
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LEUKOCYTE RECRUITMENT, ENDOTHELIAL CELL ADHESION MOLECULES, AND TRANSCRIPTIONAL CONTROL
INSIGHTS FOR DRUG DISCOVERY |
By: |
Tucker Collins (Editor) |
Format: |
Paperback |
List price:
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£139.99 |
We currently do not stock this item, please contact the publisher directly for
further information.
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ISBN 10: |
1461356172 |
ISBN 13: |
9781461356172 |
Publisher: |
SPRINGER-VERLAG NEW YORK INC. |
Pub. date: |
5 November, 2012 |
Edition: |
Softcover reprint of the original 1st ed. 2001 |
Pages: |
340 |
Synopsis: |
The localized attachment of circulating leukocytes to endothelium has been recognized as the cellular hallmark of the inflammatory response. This adhesive interaction, a necessary antecedent to the emigration of leukocytes from the blood into the tissues, is mediated by vascular adhesion molecules. Leukocyte Recruitment, Endothelial Cell Adhesion Molecules and Transcriptional Control: Insights for Drug Discovery outlines some of the cellular and molecular mechanisms of inflammation with contributions from top researchers. This volume provides an overview of three of these endothelial adhesion molecules, as examples of key mediators of leukocyte recruitment. It reviews the structure and regulation of these cell surface proteins and focus on the rapidly expanding field of transcriptional regulation of these inducible proteins, and closes with a discussion of drug discovery possibilities that target the regulation of leukocyte recruitment. This book will be of interest for any researchers, in academia or industry, looking for an overview of leukocyte recruitment or novel approaches to drug discovery. |
Illustrations: |
biography |
Publication: |
US |
Imprint: |
Springer-Verlag New York Inc. |
Returns: |
Returnable |
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Clinical Chemistry (Paperback / softback)
By:
William J., MA, PhD, MSc, MBBS, FRCP, FRCPath, FRCPEdin, FRSB, FRSC, Dr. Marshall
Elsevier Health Sciences
Our Price :
£44.99
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Ramadan and Eid al-Fitr
A celebratory, inclusive and educational exploration of Ramadan and Eid al-Fitr for both children that celebrate and children who want to understand and appreciate their peers who do.
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