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Item Details
Title: ADP-RIBOSYLATION: METABOLIC EFFECTS AND REGULATORY FUNCTIONS
By: Joel Moss (Editor), Peter Zahradka (Editor)
Format: Paperback

List price: £314.50


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ISBN 10: 1461361206
ISBN 13: 9781461361206
Publisher: SPRINGER-VERLAG NEW YORK INC.
Pub. date: 12 October, 2012
Edition: Softcover reprint of the original 1st ed. 1994
Series: Developments in Molecular and Cellular Biochemistry 12
Pages: 255
Description: Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADP-ribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other post-translational modifications such as phosphorylation, has not been generally recognized.
Synopsis: Considering the current interest in cellular regulation and intracellular signalling systems, it is surprising that the contribution of ADP-ribosylation reactions to the modulation of a variety of specific cell processes, in parallel with other post-translational modifications such as phosphorylation, has not been generally recognized. While it is not feasible to cover all aspects of ADP-ribosylation, the thirty-one articles contained in this volume provide a valuable overview of recent progress in the field within the context of cell control mechanisms. For the convenience of the reader, the various topics have been grouped into several sections: (a) poly(ADP-ribosyl)ation; (b) mono-ADP-ribosylation; (c) toxin mono-ADP-ribosylation; (d) inhibitors and activators; (e) protein modification with ADP-ribose and its analogues; and (f) non-modification forms of ADP-ribose. The contents of the individual chapters reflect the ideas of the contributors, many of whom have spent their careers attempting to resolve the biological functions of ADP-ribosylation. We hope that this publication will serve as a useful reference for those investigators that are new to the area as well as those who are actively studying ADP-ribosylation.
Illustrations: VI, 255 p.
Publication: US
Imprint: Springer-Verlag New York Inc.
Returns: Returnable
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