SIGNALING PATHWAYS IN CANCER PATHOGENESIS AND THERAPY by David A. Frank (Editor) ( 9781461412151 )

Item Details

Title:

SIGNALING PATHWAYS IN CANCER PATHOGENESIS AND THERAPY

By:

Format:

Hardback

List price:	£129.99
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ISBN 10:

1461412153

ISBN 13:

9781461412151

Publisher:

SPRINGER-VERLAG NEW YORK INC.

Pub. date:

12 November, 2011

Edition:

2012

Pages:

148

Description:

This book describes research suggesting that abnormal activation of signaling pathways is a critical event in cancer pathogenesis, and describes the emerging ability to design small molecules, protein therapeutics, and other forms of targeted cancer therapies.

Synopsis:

In recent years, increasing evidence has suggested that abnormal activation of signaling pathways is a critical event in cancer pathogenesis. In particular, activation of these pathways can lead to inappropriate cellular survival, proliferation, pluripotency, invasion, metastasis, and angiogenesis. Thus, understanding the mechanisms by which signaling pathways become subverted in a cancer cell can provide insight into critical events in cancer pathogenesis. Furthermore, as our ability to target specific molecular interactions advances, we now have the ability to design small molecules, protein therapeutics, and other forms of targeted therapies. By focusing on the specific molecular abnormalities in a cancer cell, these agents hold the potential to be much more effective and much less toxic than current cytotoxic therapies.

Illustrations:

VIII, 148 p.

Publication:

Imprint:

Springer-Verlag New York Inc.

Returns:

Returnable

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