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Item Details
Title: CHEMOTACTIC CYTOKINES
BIOLOGY OF THE INFLAMMATORY PEPTIDE SUPERGENE FAMILY
By: J. Westwick (Editor), I. J. D. Lindley (Editor), S. Kunkel (Editor)
Format: Paperback

List price: £54.99


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ISBN 10: 1468460110
ISBN 13: 9781468460117
Publisher: SPRINGER-VERLAG NEW YORK INC.
Pub. date: 6 April, 2012
Edition: Softcover reprint of the original 1st ed. 1991
Series: Advances in Experimental Medicine and Biology 305
Pages: 180
Description: Proceedings of the Second International Symposium on Chemotactic Cytokines, held in London, UK, June 25--26, 1990
Synopsis: The existence of a new family of chemotactic cytokines was realised in 1987 following the isolation and structural determination by several groups of a peptide consisting of 72 amino acids which was a potent activator of neutrophils and a chemotactic agent for lymphocytes. The first symposium of this series was held at the Royal College of Surgeons of England in December 1988, entitled Novel Neutrophil Stimulating Peptides, and brought together the majority of the laboratories which had published in this area, see Immunology Today 10: 146-147(1989). Since the first symposium there has been a dramatic increase in our knowledge of the biology of this family of structurally related peptides. The Second International Symposium on Chemotactic Cytokines was held at the Royal College of Surgeons of England in June 1990. The aim of this symposium was to provide both a forum for discussion and to determine whether this knowledge can be utilised in the design of novel therapeutic strategies for the treatment of inflammatory disorders.Although the majority of studies have been concerned with the regulation of these peptides at the molecular and cellular level, there is now evidence to suggest that specific members of this superfamily have a role in the pathogenesis of a number of diverse diseases including arthritis, psoriasis, atherosclerosis, wound repair, inflammatory lung diseases and glomerulonephritis.
Illustrations: biography
Publication: US
Imprint: Springer-Verlag New York Inc.
Returns: Returnable
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