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Item Details
Title: LIPID OXIDATION IN HEALTH AND DISEASE
By: Corinne M. Spickett (Editor), Henry Jay Forman (Editor)
Format: Electronic book text

List price: £103.00


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ISBN 10: 1482202867
ISBN 13: 9781482202861
Publisher: TAYLOR & FRANCIS LTD
Pub. date: 3 March, 2015
Series: Oxidative Stress and Disease
Pages: 440
Synopsis: Oxidative modification of lipids and phospholipids-including radical damage, halogenation, and nitration-result in significant changes to the chemical properties of the molecules, which in turn have a major effect on their biochemical functions. Lipid oxidation has long been regarded as a deleterious process responsible for lipid rancidity, loss of function, and generation of toxic products. However in recent years, research has also focused on the non-detrimental physiological and pathological effects of these chemical reactions. Lipid Oxidation in Health and Disease provides an up-to-date review of the role of oxidized lipid products in physiological and pathophysiological processes.Covering the diverse topics that contribute to research in this important field, this book explores:The mechanisms of lipid oxidation, both enzymatic and non-enzymaticAntioxidant defenses and lipid oxidationLipid oxidation products and cell signalingThe roles of oxidized lipids in specific diseases-including cardiovascular, neurodegenerative, and metabolic disorders, as well as in cancerDrug targeting and the therapeutic potential of oxidized lipidsAccurate measurement of the formation of lipid oxidation products and investigation of their biological effects and roles in disease are critical to biomedical science and new targeted therapeutics. Written by acknowledged experts in the field, this book provides a broad survey of both established knowledge and recent findings on the action of oxidized lipid products on cell signaling and gene expression in health and disease. ?
Illustrations: 8 Tables, black and white; 96 Illustrations, black and white
Publication: UK
Imprint: CRC Press
Returns: Non-returnable
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