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Item Details
Title: IN VITRO APPROACHES FOR THE EVALUATION OF DRUG EFFICACY AND TOXICITY
By: Albert P. Li
Format: Electronic book text

List price: £36.99


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ISBN 10: 1482274132
ISBN 13: 9781482274134
Publisher: TAYLOR & FRANCIS LTD
Pub. date: 26 September, 2006
Pages: 368
Synopsis: Based on the author's 20 of years of experience, this book covers the application of in vitro experimental systems in the evaluation of ADME-tox drug properties. The author dissects the reasons for clinical failure of potential drugs and discusses the importance of ADME-tox properties in clinical success. He describes current understanding of the mechanisms ADME-tox properties as a basis for in vitro assays. He highlights the importance of using human-based in vitro experimental systems to predict human in vivo outcomes. The book concludes with reviews on the state-of-the-art of in silico and genomic/proteomic experimental systems as promising approaches for the future.
Illustrations: 30 Illustrations, black and white
Publication: UK
Imprint: CRC Press
Returns: Non-returnable
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