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Item Details
| Title:
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GENOMIC INSTABILITY AND CANCER METASTASIS
MECHANISMS, EMERGING THEMES, AND NOVEL THERAPEUTIC STRATEGIES |
| By: |
Chris Maxwell (Editor), Cal Roskelley (Editor) |
| Format: |
Paperback |
| List price:
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£109.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3319352954 |
| ISBN 13: |
9783319352954 |
| Publisher: |
SPRINGER INTERNATIONAL PUBLISHING AG |
| Pub. date: |
10 September, 2016 |
| Edition: |
Softcover reprint of the original 1st ed. 2015 |
| Series: |
Cancer Metastasis - Biology and Treatment 20 |
| Pages: |
247 |
| Synopsis: |
Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse. This book connects cancer metastasis with genomic instability in a comprehensive manner. Section 1 outlines the fundamental mechanisms responsible for these cellular and tissue phenotypes. Section 2 discusses in silico, in vitro, and in vivo models used for the experimental study of these processes. Section 3 reviews emerging themes (ex., microenvironment, mechanotransduction, and immunomodulation), and Section 4 highlights new therapeutic approaches to overcome the unique challenges presented by the heterogeneous and metastatic tumor. This book is intended for undergraduates and postgraduates with an interest in the areas of medicine, oncology, and cancer biology as well as for the content expert searching for thorough reviews of current knowledge in these areas. |
| Illustrations: |
1 black & white illustrations, 18 colour illustrations, 5 black & white |
| Publication: |
Switzerland |
| Imprint: |
Springer International Publishing AG |
| Returns: |
Returnable |
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