SYSTEMS BIOLOGY by Jens Nielsen (Editor), Stefan Hohmann (Editor), Sang Yup Lee ( 9783527696154 )

Item Details

Title:

SYSTEMS BIOLOGY

By:

Jens Nielsen (Editor), Stefan Hohmann (Editor), Sang Yup Lee

Format:

Electronic book text

List price:	£126.00
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ISBN 10:

3527696156

ISBN 13:

9783527696154

Publisher:

JOHN WILEY AND SONS LTD

Pub. date:

15 March, 2017

Series:

Advanced Biotechnology

Pages:

600

Synopsis:

Comprehensive coverage of the many different aspects of systems biology, resulting in an excellent overview of the experimental and computational approaches currently in use to study biological systems. Each chapter represents a valuable introduction to one specific branch of systems biology, while also including the current state of the art and pointers to future directions. Following different methods for the integrative analysis of omics data, the book goes on to describe techniques that allow for the direct quantification of carbon fluxes in large metabolic networks, including the use of 13C labelled substrates and genome-scale metabolic models. The latter is explained on the basis of the model organism Escherichia coli as well as the human metabolism. Subsequently, the authors deal with the application of such techniques to human health and cell factory engineering, with a focus on recent progress in building genome-scale models and regulatory networks. They highlight the importance of such information for specific biological processes, including the ageing of cells, the immune system and organogenesis. The book concludes with a summary of recent advances in genome editing, which have allowed for precise genetic modifications, even with the dynamic control of gene expression. This is part of the Advances Biotechnology series, covering all pertinent aspects of the field with each volume prepared by eminent scientists who are experts on the topic in question.

Publication:

Imprint:

Wiley-VCH Verlag GmbH

Returns:

Non-returnable

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