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Item Details
| Title:
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CHIRURGISCHES FORUM'80
FUR EXPERIMENTELLE UND KLINISCHE FORSCHUNG, 97. KONGRESS DER DEUTCHEN GESELLSCHAFT FUR CHIRURGIE, MUNCHEN, 14. BIS 17. MAI 1980 |
| By: |
F. Linder, H. D. Roher, U. Mittmann |
| Format: |
Paperback |
| List price:
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£46.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3540100350 |
| ISBN 13: |
9783540100355 |
| Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
| Pub. date: |
1 May, 1980 |
| Series: |
Deutsche Gesellschaft fur Chirurgie 80 |
| Pages: |
336 |
| Language: |
ger, eng |
| Synopsis: |
22 polytraumatisierte und septische Patienten einer Intensiv- station wurden im Rahmen einer Doppelblindstudie mit Pirenzepin bzw. Placebo behandelt. Alle Patienten wurden wahrend des Beob- achtungszeitraumes in 14 Tagen dreimal endoskopiert. Ohne Pro- phylaxe waren 100% StreB-Lasionen zu beobachten, 60% wiesen Blu- tungen auf. Eine prophylaktische, intravenose Pirenzepin-Gabe hatte einen eindeutig protektiven Effekt im Hinblick auf die StreB-Blutung, Anzahl und Schweregrad der StreB-Lasionen. Summary Twenty-two severely ill patients with multinle injuries and sepsis were treated with IV pirenzepin or placebo 3 x 10 mg per day in the frame of the double-blind study. All the patients were examined three times with endoscopy during the 14-day ob- servation period. In 100% of cases without prophylactic treat- ment, stress lesions were observed, 60% of these cases had bleeding. A prophylactic IV pirenzepin application had an un- mistakable protective effect regarding the stress bleeding, number and degree of stress lesions. Literatur 1. BRODIE, D.A.: Experimental peptic ulcer. Gastroenterology 55, 125-134 (1968) 2. EINIG, D.: Ein neuer Sekretionshemmer.Ergebnisse einer Wir- kungs- und Vertraglichkeitsprufung mit Gastrozepin. Therapie- woche 27,1630-1638 (1977) 3. HASTINGS, P.R., SKILLMAN, J.J., BUSHNELL, L.J. et al.: Antacid titration in the prevention of acute gastrointestinal bleeding: a controlled randomized trial in 100 critically ill patients. |
| Illustrations: |
7 black & white illustrations, biography |
| Publication: |
Germany |
| Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
| Returns: |
Returnable |
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