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Item Details
Title:
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ORIGINS OF DEPRESSION
REPORT OF THE DAHLEM WORKSHOP ON THE ORIGINS OF DEPRESSION: CURRENT CONCEPTS AND APPROACHES BERLIN 1982, OCT.31 - NOV. 5 |
By: |
S. A. Checkley, J. Angst, J. Angst (Editor) |
Format: |
Hardback |
List price:
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£72.00 |
We currently do not stock this item, please contact the publisher directly for
further information.
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ISBN 10: |
3540124519 |
ISBN 13: |
9783540124511 |
Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
Pub. date: |
1 September, 1983 |
Series: |
Dahlem Workshop Report / Life Sciences Research Report 26 |
Pages: |
484 |
Synopsis: |
3 and a fraction mayor may not respond to treatment. On the behavioral level, animal research shows that a variety of experimental conditions can induce de- pression. The same is true in the field of treatment, where pharmacologically highly different drugs can equally alleviate depression in animals and hu- mans. The question as to whether this is due to a heterogeneity of depressive subjects based on different pathogenetic mechanisms is open to discussion. We can look for common features of all possible causal factors in the hope of finding a single basic mechanism. Many divergent findings may also be ex- plained as peripheral changes of a highly complicated dynamic system. In the field of psychopharmacology, a circular reasoning has become evident in the sense that originally the clinical antidepressive response was founded on empirical grounds only. In a second step, an attempt was made to characterize some clinically active compounds pharmacologically, and in a third, further compounds were developed based on aspects of the pharmaco- logical profiles.Moreover, the post hoc development of a pharmacological screening method has the serious disadvantage of delaying breakthroughs into new fields. |
Illustrations: |
biography |
Publication: |
Germany |
Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
Returns: |
Returnable |
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