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Item Details
Title: GENETIC APPROACHES TO CORONARY HEART DISEASE AND HYPERTENSION
By: K. Berg (Editor), Victor Bulyzhenkov (Editor), P. Corvol (Editor)
Format: Hardback

List price: £72.00


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ISBN 10: 3540544763
ISBN 13: 9783540544760
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Pub. date: 3 December, 1991
Pages: 173
Description: An examination of the manner in which modern genetic techniques have resulted in the identification of polymorphic markers involved in the normal regulation and function of the cardiovascular system. The text explores genes which may contribute to the risk of heart disease and hypertension.
Synopsis: Cardiovascular diseases are the principal cause of mortality in many developed countries and are increasing in importance in developing countries where communicable diseases are being brought under control. It is estimated that coronary heart disease (CRD) and cerebrovascular diseases are responsible for between 40-50% of all deaths. Righ blood pressure is common in all industrialized societies and contributes importantly to CRD. It is well known that genetic factors play an important role in the etiology and pathogenes es of cardiovascular diseases and contribute to an individual's susceptibility or resistance to the disease. The application of modern genetic techniques has resulted in the identification of polymorphie markers that are involved in the normal regulation and function of the cardiovascular system. Many of these may contribute to the individual differences in the risk for CRD and hypertension. It is now known that several risk factors or protective factors with respect to cardiovascular diseases are strongly influenced by genes, and it is now possible to identify individual genes contributing to cardiovascular risk.A large bank of genetic knowledge relevant to CRD and hypertension has become available during the past years. As a result, it is now believed that CRD, for example, could be a good model for a feasibility study to determine a way by which preventive measures can be applied.
Illustrations: 17 black & white illustrations, 29 black & white tables, biography
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Returnable
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