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Item Details
Title: ARTIFICIAL LIVER SUPPORT
CONCEPTS, METHODS, RESULTS
By: M. Mito (Editor), Katsuya Akamatsu, Hideo Aoki
Format: Hardback

List price: £72.00


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ISBN 10: 3540552588
ISBN 13: 9783540552581
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Pub. date: 11 January, 1993
Edition: 2nd Revised edition
Pages: 466
Description: This overview of artificial liver support presents the current knowledge of liver failure and regeneration, clinical methods used in treatment, new experimental methods of treatment, an overview of the present status of liver transplanation and possible future developments.
Synopsis: Continuing progress has been made since the first edition of Artificial Liver Support was published. Liver transplantation has however become an estab- lished therapy for a relatively small number of patients who remain patients for life. There therefore continues to be a great need for the development of other forms of artificial liver support. Improved intensive care utilizing improved plasma exchange, dialysis, sclerotherapy, and intracranial pressure monitoring have improved survival in fulminant hepatic failure. Progress has also been made in lipid membrane detoxification, in cell cultures, and in cell transplantation, and the isolation of various liver cell growth factors has led to deep insight into the mechanisms of liver regeneration. This book gives the clinician and the researcher detailed information about established new methods of clinic work and laboratory research, and describes new experimental approaches indicating the direction of future research. G. BRUNNER M. Mno Preface to the First Edition The regenerative capacity of the liver cell is almost unlimited.Therefore after acute liver damage, be it viral, toxic, hypoxic, or surgical in origin, restitutio ad integrum is the usual outcome. In two forms of liver disease, however, this is not the case: in fulminant hepatic failure, liver regeneration often is not fast enough to keep the organism alive; in end-stage cirrhosis, regeneration is disturbed by a hypertrophic architecture of fibrotic tissue. For these extreme forms of liver disease and for critical situations before and after liver surgery, artificial liver support is needed.
Illustrations: 50 black & white tables, biography
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Returnable
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