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Item Details
| Title:
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GROWTH HORMONE AND SOMATOMEDINS DURING LIFESPAN
6TH CONGRESS : PAPERS |
| By: |
Eugenio E. Muller (Editor), Daniela Cocchi (Editor), Vittorio Locatelli (Editor) |
| Format: |
Hardback |
| List price:
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£72.00 |
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We believe that this item is permanently unavailable, and so we cannot source
it.
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| ISBN 10: |
3540566902 |
| ISBN 13: |
9783540566908 |
| Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
| Pub. date: |
26 October, 1993 |
| Pages: |
358 |
| Description: |
An analysis of the action and function of growth hormones and insulin-like growth factors as well as the potential uses of the hormone and its dependent peptides in a number of physiological and pathological conditions. |
| Synopsis: |
The various congresses on growth hormone (GH) which have been held in Milan since 1967, the Milan Congresses, have witnessed over 25 years the tremendous expansion of a research field that was based initially upon the scarce knowledge of the biological properties of a protein. GH, whose chemical structure had just been identified and a radioimmunoassay developed for its measurement in blood, became in the following years a major area of biological research. The boundaries have since become blurred, as the research area has extended to the physiology and pathology of growth, puberty and reproduction, and the control of metabolism during the whole lifespan. Since the last GH Congress held in 1987, GH studies using the molecular biological approach have resulted in the puri- fication, cloning and expression of the human GH (hGH) recep- tor and binding protein, in new and exciting information on the insulin-like growth factors (IGF) and their paracrine and autocrine roles, and in the awareness that a panoply of binding proteins are present in the extracellular fluids and can, possibly, modulate IGF-receptor interactions and, thus, IGF actions.Finally, the availability of large amounts of biosynthetic hGH, besides allow- ing more extensive clinical use in states of GH deficiency and extrasomatotrophic pathologies, has permitted disclosure of im- portant metabolic effects of hGH during adulthood and, perhaps, aging and in many protein catabolic states. |
| Illustrations: |
22 black & white illustrations, 26 black & white tables, biography |
| Publication: |
Germany |
| Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
| Returns: |
Returnable |
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