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Item Details
Title: ANTISENSE STRATEGIES FOR THE STUDY OF RECEPTOR MECHANISMS
By: Robert B. Raffa (Editor), Frank Porreca (Editor)
Format: Hardback

List price: £56.99


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ISBN 10: 3540611541
ISBN 13: 9783540611547
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Pub. date: 26 August, 1996
Series: Neuroscience Intelligence Unit
Pages: 238
Description: This volume is about antisense oligonucleotides and their use to investigate the mechanisms of drug action. It covers the basic concepts of antisense strategy. The applications presented include in-vitro biochemical studies, in-vivo receptor sub-typing and G-protein coupling.
Synopsis: This book is about antisense oligonucleotides and their use in investigating mechanisms of drug action. It covers the basic concepts of antisense strategy and contains examples of how this new approach can be utilized to study receptors, and the transduction and mediation of drug actions. A wide spectrum of applications is presented, including in-vitro biochemical studies, in-vivo receptor sub-typing and G-protein coupling, and behavioral studies. The detailed methodology of each of these applications is given (including the antisense nucleotide sequences), as well as results, hypotheses, speculations and related caveats. A resource for both the novice and the experienced researcher, providing the general concepts of this emerging field as well as specific examples of advantages and benefits.
Illustrations: 49 figures, 9 tables
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Returnable
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