Title:
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REDIRECTION OF TH1 AND TH2 RESPONSES
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By: |
R. L. Coffman (Editor), Sergio Romagnani (Editor) |
Format: |
Hardback |

List price:
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£72.00 |
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ISBN 10: |
3540650482 |
ISBN 13: |
9783540650485 |
Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
Pub. date: |
15 December, 1998 |
Series: |
Current Topics in Microbiology and Immunology Vol 238 |
Pages: |
159 |
Description: |
The articles in this volume review basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; and the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases. |
Synopsis: |
The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance. |
Illustrations: |
8 black & white illustrations, 10 black & white tables, biography |
Publication: |
Germany |
Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
Returns: |
Returnable |
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