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Item Details
Title: REDIRECTION OF TH1 AND TH2 RESPONSES
By: R. L. Coffman (Editor), Sergio Romagnani (Editor)
Format: Hardback

List price: £72.00


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ISBN 10: 3540650482
ISBN 13: 9783540650485
Publisher: SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG
Pub. date: 15 December, 1998
Series: Current Topics in Microbiology and Immunology Vol 238
Pages: 159
Description: The articles in this volume review basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; and the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases.
Synopsis: The two major subsets of CD4+ helper T cells, designated Th1 and Th2, have quite different patterns of cytokine production and, as a consequence, have very different roles in immune responses. The articles in this volume review both basic and clinical studies of T cell heterogeneity, including: the mechanisms by which Th1 and Th2 cells develop and maintain their differences in cytokine production; the different roles of Th1 and Th2 cells in allergy, autoimmunity and infectious diseases; the prospects and strategies for therapeutic manipulation of Th1 and Th2 cells; and the control of Th1 and Th2 responses by regulatory T cell subsets. The volume should give the reader a view of the development and function of Th1 and Th2 cells and the attempts to treat immunological diseases with therapies directed towards altering the Th1/Th2 balance.
Illustrations: 8 black & white illustrations, 10 black & white tables, biography
Publication: Germany
Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Returns: Returnable
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