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Item Details
Title: NEUROINFLAMMATORY MECHANISMS IN ALZHEIMER'S DISEASE
BASIC AND CLINICAL RESEARCH
By: J. Rogers (Editor)
Format: Hardback

List price: £137.00


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ISBN 10: 3764360747
ISBN 13: 9783764360740
Publisher: BIRKHAUSER VERLAG AG
Series: Progress in Inflammation Research
Pages: 250
Description: This volume emphasizes correlations between inflammatory phenomena in the brains of Alzheimer's disease patients with findings of the "classic" approach, such as pathophysiologic effects of amyloid b peptide. It contains both overviews of the field and focused papers on specific topics.
Synopsis: Twenty years ago, the idea that Alzheimer's disease (AD) involved any sort of inflammatory or immune component seemed implausible. Now, there are hundreds of laboratories world-wide that are pursuing basic research in this area, and multi-site clinical trials are underway. How this dramatic sea-change came about is made clear in this book, both through overviews of the field and through focused papers on specific topics of recent interest. Complement, cytokines and the complex host of other acute phase reactants are covered, as are summaries of many epidemiologic and clinical-pathological findings. Written by established investigators who have led neuroinflammatory research for two decades, this volume particularly emphasizes correlations between inflammatory phenomena in the brains of AD patients with findings of the "classic" approach, such as pathophysiologic effects of amyloid b peptide. The book documents and synthesizes earlier and recent findings in AD to help a broad range of scientists in gaining a broader and more comprehensive knowledge of the complexities AD presents.In addition, many of the concepts and results that have emerged from AD inflammation research may have implications for other neurologic disorders that involve inflammatory components, including multiple sclerosis and stroke.
Illustrations: 24 b&w and 13 duotone illustrations
Publication: Switzerland
Imprint: Birkhauser Verlag AG
Returns: Non-returnable
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