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Item Details
| Title:
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THE HYPERTROPHIED HEART
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| By: |
R. Jacob (Editor) |
| Format: |
Paperback |
| List price:
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£42.99 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3798504822 |
| ISBN 13: |
9783798504820 |
| Publisher: |
STEINKOPFF DARMSTADT |
| Pub. date: |
1 January, 1977 |
| Pages: |
232 |
| Description: |
Reprinted from Basic research in cardiology, v. 72, no. 2/3, Mar.-June, 1977. |
| Synopsis: |
Die Umkehr der Calcium-Pumpe des myokardialen sarkoplasmatischen Retikulums (SR) wurde untersucht. SR-Vesikel, die passiv durch Prliinkubation mit hohen Calciumkonzentrationen mit Calcium beladen wurden, synthetisieren ATP aus Orthophosphat und ADP. Die ATP-Synthese erfolgt tiber die Phos phorylierung der Calcium-Transport-ATPase des SR durch Orthophosphat und eine Dephosphorylierung des E '""" P durch ADP. Die Rate der Calcium-Frei setzung aus SR-Vesikel - die Calcium-Beladung erfolgte aktiv in Gegenwart von Acetylphosphat - wird durch ADP erhoht. Der ADP-abhlingige Calcium Efflux ist stochiometrisch mit der ATP-Synthese aus Orthophosphat und ADP gekoppelt. References 1. Suko, J.: The calcium pump of cardiac sarcoplasmic reticulum. Functional alterations at different levels of thyroid state in rabbits. J. Physiol. 228, 563 (1973). 2. Hasselbach, W.: Sarcoplasmic Membrane. ATPase. In: The Enzymes (P. D. Boyer, eds.), N. Y. 10, 431 (1974). 3. Pang, D. C., N. F. Briggs: Reaction mechanism of cardiac sarcotuble calcium dependent adenosin triphosphatase. Biochemistry 12, 4905 (1973). 4. Suko, J., W. Hasselbach: Properties of a phosphorylated intermediate of the 2 Ca -dependent ATPase and ADP-ATP phosphate exchange of cardiac sarco plasmic reticulum. Naunyn-Schmiedeberg's Arch. Pharmakol. expo Pathol. 282, R. 97 (1974). 5. Suko, J., W. Hasselbach: Characterization of cardiac sarcoplasmic reticulum ATP-ADP phosphate exchange and phosphorylation of the calcium trans port adenosin triphosphatase. Europ. J. Biochem. 64, 123 (1976). 2 2 6. Suko, J.: The effect of temperature on Ca +-uptake and Ca +-activated ATP hydrolysis by cardiac sarcoplasmic reticulum. Experientia 29, 396 (1973). |
| Illustrations: |
black & white illustrations |
| Publication: |
Germany |
| Imprint: |
Steinkopff Darmstadt |
| Returns: |
Returnable |
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