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Item Details
| Title:
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IMMUNE TOLERANCE AND THE TREATMENT OF HEMOPHILIACS WITH AN INHIBITOR
WORKSHOP, ROME, AUGUST 1994: PROCEEDING |
| By: |
Giuliano Mariani (Editor), H. H. Brackmann (Editor) |
| Format: |
Paperback |
| List price:
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£19.10 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3805562977 |
| ISBN 13: |
9783805562973 |
| Publisher: |
S KARGER AG |
| Pub. date: |
1 February, 1996 |
| Series: |
Vox Sanguinis v. 70, Supplement 1 |
| Pages: |
80 |
| Description: |
This work reviews the epidemiology and pathophysiology of FVII inhibitors, and the mechanisms leading to immune tolerance. It covers the various treatment protocols applied worldwide, clinical issues as well as economic and organizational aspects. |
| Synopsis: |
A major complication preventing adequate treatment of haemophilia patients is the development of inhibitory antibodies against factor VIII. In this case, one of the best therapeutic approaches currently available is the induction of immune tolerance, a method first described in 1976. Immune tolerance can be restored in most haemophiliacs who have developed an inhibitor through the administration of high doses of factor VIII, making it possibe to treat bleeding episodes with normal quantities of factor VIII, to increase the patient's survival chances and to reduce the cost of further treatment. Presenting the proceedings of an international workshop, this publication reviews the epidemiology and pathophysiolosy of FVIII inhibitors, and the mechanisms leading to immune tolerance. Covering the various treatment protocols applied worldwide, clinical issues as well as economic and organizational aspects, it provides essential information for doctors treating haemophiliacs and all those working in the fields of haematology, immunology, pharmacology, paediatrics and blood transfusion. |
| Illustrations: |
16, 16 fig., 37 tab. |
| Publication: |
Switzerland |
| Imprint: |
S Karger AG |
| Returns: |
Non-returnable |
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