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Item Details
Title: ADVANCES IN NUCLEAR ARCHITECTURE
By: Niall M. Adams (Editor), Paul Simon Freemont (Editor)
Format: Hardback

List price: £179.99


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ISBN 10: 9048198984
ISBN 13: 9789048198986
Publisher: SPRINGER
Pub. date: 19 October, 2010
Edition: 2011 ed.
Pages: 210
Description: Advances in Nuclear Architecture presents the principles of nuclear architecture, covering the fundamentals, image processing, quantitative analysis, and applications related to disease. The text focuses on the most recent breakthroughs, and emphasizes a rigorous development of the scientific process.
Synopsis: This book provides a snapshot of the state-of-the art in the study of mammalian cell nuclear architecture, and features a diverse range of chapters written by top researchers. A key aspect is an emphasis on precise and repeatable quantitative analysis and simulation in addition to the more familiar biological perspective. The fusion of such material frames the future of the discipline. Quantitative contributions stress reproducible and robust 3D analysis, using a variety of tools ranging from point pattern analysis to shape registration methods. Biological insights include the role of nuclear subdomains in cancer, nuclear molecular motors, and a holistic view of gene transcription.
Illustrations: VII, 210 p.
Publication: Netherlands
Imprint: Springer
Returns: Returnable
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