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Item Details
| Title:
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PROTEOLYSIS IN CELL FUNCTIONS
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| By: |
V.K.Hopsu- Havu (Editor), M. Jarvinen (Editor), Heidrun Kirschke (Editor) |
| Format: |
Hardback |
| List price:
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£59.00 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
9051993226 |
| ISBN 13: |
9789051993226 |
| Publisher: |
IOS PRESS |
| Pub. date: |
1 January, 1997 |
| Series: |
Biomedical and Health Research Vol 13 |
| Pages: |
592 |
| Description: |
This work examines the ways in which proteolytic enzymes have an esential function in all cells. New aspects are considered, such as: structure of proteases and mechanisms of protein degradation; functions and properties of proteases and inhibitors; signal peptidases; and autophagy. |
| Synopsis: |
The proteolytic enzymes have an essential function in all cells. Their activities are regulated by the rate of synthesis, activation of proenzymes and by the rate of synthesis of their inhibitors. They are synthesized in ribosomes like any other proteins and transported to various storage organelles or secreted from the cells and are activated in the pericellular space or in interstitium. Various cells and tissues have their characteristic enzyme patterns which serve their specific functions. Proteolytic enzymes take part and often have a regulatory role in numerous phases of cell function, e.g. cell division, migration, apoptotic as well as necrotic cell death etc. Diseases in which proteolysis has been subject of active research are e.g. cancer metastasis, viral infections, e.g. HIV, and Alzheimer's disease. They are also an essential part in any tissue remodelling, wound healing, throughout the kingdom of fauna and flora. |
| Illustrations: |
black & white illustrations |
| Publication: |
US |
| Imprint: |
IOS Press,US |
| Returns: |
Non-returnable |
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