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Item Details
| Title:
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MONOAMINE OXIDASE
BASIC AND CLINICAL ASPECTS |
| By: |
T. Nagatsu, Hasan Parvez, H. Yasuhara (Editor) |
| Format: |
Hardback |
| List price:
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£118.00 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
9067641464 |
| ISBN 13: |
9789067641463 |
| Publisher: |
BRILL |
| Pub. date: |
1 January, 1993 |
| Pages: |
248 |
| Description: |
Contains up-to-date studies of both basic research and applications in the areas of monoamine oxidase (MAO) research - the determination of the nucleotide sequence coding two forms of human MAO (MAO-A and MAO-B), and the involvement of MAO in potent dopaminergic neurotoxicity of MPTP. |
| Synopsis: |
Monoamine oxidase (MAO), a mitochondrial enzyme which metabolizes monoamines in both the central nervous system and peripheral tissues, plays an important role in the regulation of neuronal activities by controlling the concentrations of monoamines. During the past three decades the enzymological properties of MAO have been studied extensively. The most exciting and important advances in these studies have been the determination of the nucleotide sequence coding two forms of human MAO (MAO-A and MAO-B), and the involvement of MAO in potent dopaminergic neurotoxicity of MPTP, which had led to the acceleration of aetiological studies of Parkinson's disease. Other aspects of MAO studies have been the application of selective and safe MAO inhibitors in the treatment of depression and Parkinson's disease as well as the correlation between MAO and several psychiatric and neurodegenerative disorders. |
| Publication: |
Netherlands |
| Imprint: |
VSP International Science Publishers |
| Returns: |
Non-returnable |
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