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Item Details
Title: PROTEINASE AND PEPTIDASE INHIBITION
RECENT POTENTIAL TARGETS FOR DRUG DEVELOPMENT
By: H. John Smith (Editor), Claire Simons (Editor)
Format: Hardback

List price: £220.00
Our price: £198.00
Discount:
10% off
You save: £22.00
ISBN 10: 0415273498
ISBN 13: 9780415273497
Availability: Usually dispatched within 1-3 weeks.
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Stock: Currently 0 available
Publisher: TAYLOR & FRANCIS LTD
Pub. date: 28 March, 2002
Pages: 440
Description: A valuable reference book that will appeal to both academic and industrial researchers in the fields of medicinal chemistry, drug design and development, pharmacology, biochemistry and molecular and cell biology.
Synopsis: Cellular proteinases and their physiological role in normal and disease states have been the subject of great interest over recent decades. At present, specific protease inhibitors are exploited both as tools in unraveling the role of individual proteinases in particular cellular processes and for the development of chemotherapeutic agents for the treatment of various disorders. Proteinase and Peptidase Inhibition presents updated progress reports on the characterization of a wide range of cellular proteinases whose inhibitors may hold the key to the development of new drugs. Introductory chapters deal with the broad enzyme classes, inhibitor types and regulatory mechanisms governing proteinase activity. The target enzymes themselves, together with all aspects of their inhibition and inhibitor design, are comprehensively described. The classification of target enzymes by structural similarity, rather than by pharmacological effects, provides a new and coherent platform for understanding how inhibition of different targets can lead to the same therapeutic outcomes.This is a valuable reference book that will appeal to both academic and industrial researchers in the fields of medicinal chemistry, drug design and development, pharmacology, biochemistry, and molecular and cell biology.
Illustrations: 100 b&w line drawings, 46 tables
Publication: UK
Imprint: Taylor & Francis Ltd
Returns: Returnable
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DESIGN OF CASPASE INHIBITORS AS POTENTIAL CLINICAL AGENTS (HB)
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HARES AND TAILS OF SHADOW WOOD (PB)
NUCLEOSIDE MIMETICS
NUCLEOSIDE MIMETICS (HB)
PROTEIN MISFOLDING IN NEURODEGENERATIVE DISEASES
PROTEIN MISFOLDING IN NEURODEGENERATIVE DISEASES (HB)
PROTEINASE AND PEPTIDASE INHIBITION
PROTEINASE AND PEPTIDASE INHIBITION
PROTEINASE AND PEPTIDASE INHIBITION
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PROTEINASE AND PEPTIDASE INHIBITION
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