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Item Details
Title: PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 31
By: Dennis A. Smith, Han van de Waterbeemd, Don K. Walker
Format: Electronic book text

List price: £108.00


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ISBN 10: 3527608281
ISBN 13: 9783527608287
Publisher: JOHN WILEY AND SONS LTD
Pub. date: 21 August, 2006
Edition: 2nd Revised edition
Series: Methods and Principles in Medicinal Chemistry 31
Pages: 207
Description: Pharmacokinetics and Metabolism in Drug Design systematically covers all stages of the fate of a drug in the human body, from absorption to excretion. The main emphasis lies on drug metabolism and drug toxicity which are the most common causes of failure in present-day drug development.
Synopsis: In this new edition of a bestseller, all the contents have been updated and new material has been added, especially in the areas of toxicity testing and high throughput analysis. The authors, all of them employed at Pfizer in the discovery and development of new active substances, discuss the significant parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. They cover everything from the fundamental principles right up to the impact of pharmacokinetic parameters on the discovery of new drugs. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects.
Publication: UK
Imprint: Wiley-VCH Verlag GmbH
Returns: Non-returnable
Some other items by this author:
ADVANCED COMPUTER-ASSISTED TECHNIQUES IN DRUG DISCOVERY, VOLUME 3
ATTRITION IN THE PHARMACEUTICAL INDUSTRY
ATTRITION IN THE PHARMACEUTICAL INDUSTRY
ATTRITION IN THE PHARMACEUTICAL INDUSTRY
ATTRITION IN THE PHARMACEUTICAL INDUSTRY (HB)
CHEMOMETRIC METHODS IN MOLECULAR DESIGN, VOLUME 2
DRUG BIOAVAILABILITY
DRUG BIOAVAILABILITY
DRUG BIOAVAILABILITY (HB)
LIPOPHILICITY IN DRUG ACTION AND TOXICOLOGY, VOLUME 4
METABOLISM, PHARMACOKINETICS AND TOXICITY OF FUNCTIONAL GROUPS (HB)
METABOLITE SAFETY IN DRUG DEVELOPMENT
METABOLITE SAFETY IN DRUG DEVELOPMENT
METABOLITE SAFETY IN DRUG DEVELOPMENT (HB)
PHARMACOKINETIC OPTIMIZATION IN DRUG RESEARCH
PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 51
PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 51
PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 51
PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 51 (HB)
REACTIVE DRUG METABOLITES (HB)
STRUCTURE PROPERTY CORRELATIONS AND MOLECULAR DESIGN (HB)


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