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Item Details
| Title:
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PHARMACOKINETICS AND METABOLISM IN DRUG DESIGN, VOLUME 51
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| By: |
Dennis A. Smith (Editor), Charlotte Allerton (Editor), Amit S. Kalgutkar (Editor) |
| Format: |
Electronic book text |
| List price:
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£108.00 |
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We believe that this item is permanently unavailable, and so we cannot source
it.
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| ISBN 10: |
3527645306 |
| ISBN 13: |
9783527645305 |
| Publisher: |
JOHN WILEY AND SONS LTD |
| Pub. date: |
13 September, 2012 |
| Edition: |
3rd Revised edition |
| Series: |
Methods and Principles in Medicinal Chemistry 51 |
| Pages: |
268 |
| Description: |
Pharmacokinetics and Metabolism in Drug Design systematically covers all stages of the fate of a drug in the human body, from absorption to excretion. The main emphasis lies on drug metabolism and drug toxicity which are the most common causes of failure in present-day drug development. |
| Synopsis: |
In this new edition of a bestseller, all the contents have been brought upto-date by addressing current standards and best practices in the assessment and prediction of ADMET properties. Although the previous chapter layout has been retained, substantial revisions have been made, with new topics such as pro-drugs, active metabolites and transporters covered in detail in a manner useful to the Drug Discovery scientist. The authors discuss the parameters and processes important for the absorption, distribution and retention of drug compounds in the body, plus the potential problems created by their transformation into toxic byproducts. While aimed at all those dealing professionally with the development and application of pharmaceutical substances, the readily comprehensible style makes this book equally suitable for students of pharmacy and related subjects. Uniquely comprehensive, the book relates physicochemistry and chemical structure to pharmacokinetic properties and ultimately drug efficacy and safety. |
| Publication: |
UK |
| Imprint: |
Wiley-VCH Verlag GmbH |
| Returns: |
Non-returnable |
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